The Likelihood Ratio: An Introduction and Application
Monday September 24th, 2018 // 8:30 am - 5:00 pm // Room 612/613
Description: This workshop will give the audience an introduction to the likelihood ratio (LR) for interpreting single source and mixed DNA profiles. Attendees will become familiar with the mathematical models and calculations for the classical binary LR approach. Topics covered will include a review of basic statistics, Bayes Theorem and the LR, setting propositions, population genetic models used in forensic calculations, and an introduction to more advanced calculations for relatedness (“It was not me, but my brother”). Examples and individual/group exercises will help the attendees understand the theoretical concepts. Attendees should have a solid understanding of algebra and bring a calculator to the workshop. Handouts will be provided.
Fees include course materials, continental breakfast, breaks, and lunch.
Learning outcomes will include:
- Statistics Review (up to the 3rd Law of Probability)
- Bayes Theorem
- Setting Propositions
- Calculating LRs for Single Source Profiles (Individual and Group exercises on paper)
- Population genetics models (NRC II 4.1 and 4.2)
- Calculating LRs for Mixtures (Individual and Group exercises on paper)
- Calculating LRs for relatives as alternate contributors
- Presenting LRs and avoiding fallacies
This workshop is intended for DNA analysts, supervisors, technical leaders, attorneys and judges. A foundation in algebra is required.
Environmental Science and Research Limited (ESR) New Zealand
Jo-Anne Bright is a Senior Science Leader within the Forensic Biology group at the Institute of Environmental Science and Research Limited (ESR) New Zealand, where she has worked since 1999. Jo is one of the co developers of STRmix™, expert software for the interpretation of forensic DNA profiles and the new Australasian standard.Submit Questions
National Institute of Standards and Technology
Dr. Michael Coble is a Forensic Biologist in the Applied Genetics Group at the National Institute of Standards and Technology. His current research focuses on DNA mixture interpretation and research with lineage markers.
University of North Texas Health Science Center
In 2009 Dr. Budowle became Executive Director of the Institute of Applied Genetics and Professor at the University of North Texas Health Science Center at Fort Worth, Texas. He currently directs the Center for Human Identification. His research efforts focus on the areas of human forensic identification, microbial forensics, emerging infectious disease, molecular biology technologies, and pharmacogenetics.
Andrew Hessel is a Distinguished Researcher with Autodesk Inc. in their Life Sciences group and the CEO of Humane Genomics Inc. His work focuses on using engineered viruses for good. He is also a founding member of the GP-Write leadership team advancing the international genomics effort to write large genomes, including the human genome. Andrew is faculty at Singularity University, a global community applying exponential technologies to solving the world’s largest challenges. A dynamic and inspiring speaker, his presentations introduce people to what’s happening on the leading edge of biotechnology and bioengineering.