Application of SNP Probe Capture Enrichment and Massively Parallel Sequencing in the Analysis of Degraded and Mixed Samples
Samples that are highly degraded and mixed in nature are commonly found in mass disaster events, missing persons, and forensic casework and often pose issues with conventional short tandem repeat (STR) typing by capillary electrophoresis (CE). DNA fragment sizes less than 150 bp present issues as two intact primer binding sites may not be present […]