Completing the Circle: Forensic Analysis of the Entire Mitochondrial Genome on Ion Torrent MPS Platforms
Traditional sequencing of the mitochondrial genome in forensic labs has been limited largely to hypervariable regions (HVI and HVII) of the control region due to the high density of sequence variants and limitations with Sanger-type sequencing (STS) methodology. Massively parallel sequencing (MPS) of the entire mitochondrial genome offers forensic DNA analysts an alternative to STS. […]