Lessons Learned from Implementing and Operating a Rapid DNA Program on the United States Border

Since early 2018, the Department of Homeland Security (DHS) has encountered a migration crisis at the southern border, including an increase in fraudulent family relationship claims. To help address this, Bode Technology developed, deployed, and operated a wide-ranging program for DHS to utilize Rapid DNA to identify and deter possible child trafficking by identifying fraudulent […]

Under the Microscope – Jennifer Cihlar

Massively parallel sequencing (MPS) technologies have been extensively evaluated by forensic genomic Research and Development laboratories for the past ten years. Results from these studies have routinely demonstrated the benefits afforded by use of these enhanced technologies and have helped progress the adoption of MPS in forensic genomic laboratories that process biological evidence. The commercial […]

Under the Microscope – Dane Plaza

Rapid DNA technology can provide investigators with real-time investigative information, enhance border security and public safety, aid in prevention and detection of human trafficking, and provide identifications in mass casualty events. While Rapid DNA was designed for operation by non-technical field personnel, it is important to be implemented properly with the complementary support of trained […]

Under the Microscope – Curt Hewitt

For the past three years, Signature Science has been working on the IARPA PROTEOS program to demonstrate that protein sequencing can successfully be used for human forensic identification for samples where DNA was either absent or degraded, specifically touch samples. Together with the University of North Texas Health Science Center and The Ohio State University, […]

Under the Microscope – Allison Sherier

Over the past decade microbial forensics has shifted from solely biosecurity applications to include human identification (HID). Studies have shown that the human skin microbiome could potentially serve as an adjunct to traditional DNA evidence, especially when the human DNA is low quantity. Recently, a custom targeted panel for the human skin microbiome has been […]

Under the Microscope – Jianye Ge

Y chromosome STR haplotypes have been used in assisting forensic investigations primarily for identification and male lineage determination. The Scientific Working Group on DNA Analysis Methods (SWGDAM) Lineage Marker Committee published interpretation guidelines for Y-STR typing, which provide helpful guidance. However, these guidelines do not address the issue of kinship analysis with Y-STR haplotypes. Because […]

Under the Microscope – Lies Janssens and Emily Simek

Automated and semi-automated sample processing has become more widespread with the implementation of various robotic platforms. A new robotic application for differential separation of sexual assault samples using a novel nanofiber filter was evaluated for a high-throughput laboratory system.   At their presentation this year, Lies Janssens and Emily Simek will be presenting on a […]

Under the Microscope – Elena Zavala

DNA analysis has become an essential component for resolving unidentified human remains, disaster victim identification, and cold cases. Due to the high copy number of mitochondrial DNA (mtDNA) molecules in each cell compared to nuclear DNA, mtDNA is often used in these cases to aid with identification when nuclear DNA recovery fails. The Armed Forces […]

Under the Microscope – Lawrence Wein

The genealogy process is typically the most time-consuming part of – and a limiting factor in the success of – investigative genetic genealogy. In his presentation at ISHI, Lawrence Wein will present a systematic approach to efficiently perform the genealogy portion of investigative genetic genealogy. He and his colleagues have formulated a two-stage mathematical model […]