Applying a Casework Assessment and Interpretation Approach to Probabilistic Genotyping Results Workshop
Monday October 31st, 2022 // 8:30 am - 5:00 pm // Annapolis 1-3
This workshop will give the audience an introduction to casework assessment and interpretation (CAI) approaches for reviewing the outputs (including the likelihood ratio) and diagnostics of probabilistic genotyping software used for the analysis of forensic DNA mixtures. CAI methodology is a formal model for the evaluation of evidence in a balanced, logical, robust and transparent manner.
We will describe the various diagnostics and outputs from such software and give guidance on the assessment of results by way of examples. We will explore issues such as the number of contributors, relatives, and stochastic effects within a mixture. Handouts will be provided.
- Improved post-software interpretation of results.
- The importance of the review of diagnostics and outputs of PG software for casework.
- Provide guidance for a systematic and holistic approach to evaluating diagnostics
- Demonstrate an increased confidence for interpreting challenging samples from PG software.
This workshop is intended for DNA analysts, supervisors, technical leaders, attorneys, and judges. Attendees should be familiar with the concepts of likelihood ratios, PG software, and genotype weights.
Dr. Jo Bright will describe the various diagnostics within the STRmix report, how they are calculated, and their behavior – for both typical and atypical interpretations.
Dr. Michael Coble will describe the generation of genotype weights and likelihood ratios with PG reports.
Ms. Teresa Cheromcha will present casework examples of profiles where atypical weights and diagnostics were observed, their detection and their remediation.
Associate Director, Center for Human Identification, UNTHSC
Michael Coble, PhD, is an Associate Professor and the Associate Director of the Center for Human Identification at the University of North Texas Health Science Center in Fort Worth, Texas. He serves as a member of the OSAC Biological Data Interpretation and Reporting Committee and is an invited guest at the Scientific Working Group on DNA Analysis Methods (SWGDAM).Submit Questions
Environmental Science and Research Limited (ESR) New Zealand
Jo-Anne Bright is a Senior Science Leader within the Forensic Biology group at the Institute of Environmental Science and Research Limited (ESR) New Zealand, where she has worked since 1999. Jo is one of the co developers of STRmix™, expert software for the interpretation of forensic DNA profiles and the new Australasian standard.Submit Questions
Senior DNA Analyst, DNA Labs International
Teresa has approximately 17 years of forensic molecular biology experience. Her forensics career began at a biodefense laboratory in 2004, transitioned to human genetics in 2007 at the Armed Forces DNA Identification Laboratory, and continued in the biological sciences unit with the Colorado Bureau of Investigation from 2011-2021 where she served as the Assistant DNA Technical Leader for four years.Submit Questions