Category
Massively Parallel Sequencing
Reverse Complement PCR: A Novel System for the Target Capture of Identity SNPs for Typing Highly Degraded DNA
Rachel Kieser, former PhD student at the University of North Texas Health Science Center, shares the poster that she presented at ISHI on a new method to target degraded DNA. ...
An Interview with Dr. Peter de Knijff, a Pioneer in Forensic DNA
Leiden University’s Peter de Knijff humbly declines being called a guru, but, as a pioneer in forensic DNA, his contributions to the field have been plentiful. Dr. de...
Application of SNP Probe Capture Enrichment and Massively Parallel Sequencing in the Analysis of Degraded and Mixed Samples
Samples that are highly degraded and mixed in nature are commonly found in mass disaster events, missing persons, and forensic casework and often pose issues with conventional...
Assessing Crude Extracts from Reference Samples in Massively Parallel Sequencing Workflows
Forensic science tends to be a slow-moving field, but every so often new technology helps push forensic testing forward. Massively parallel sequencing (MPS) is one such techno...
Molecular Dissection of a Crime Scene: Introducing STR Sequencing in Routine Investigation
I currently work as a post-doctoral researcher at the Institute of Legal Medicine, Ludwig Maximilian University of Munich (LMU). My ongoing research concerns the application o...
Exploring the Value of Biogeographic Ancestry in the Absence of a DNA Database
There are many scenarios encountered in forensic casework in which bone may be the only viable sample type for DNA testing, including fires, terrorist attacks, natural disaste...
Is MPS Right for Your Forensics Lab?
Next-generation sequencing (NGS), or massively parallel sequencing (MPS), is a powerful tool for genomic research. This high-throughput technology is fast and accessible—you...
Molecular Autopsies in the Whole Genome Sequencing Era
Every year, nearly 8 million people die from sudden cardiac death, which is defined as the unexpected death of a seemingly healthy person due to malfunctions in the heart’s...
Harnessing the Power of Massively Parallel Sequencing in Forensic Analysis
The rapid advancement of next-generation sequencing technology, also known as massively parallel sequencing (MPS), has revolutionized many areas of applied research. One such ...