Embracing Single Cell Analysis in Forensic Science: Exploring the Opportunities

Embracing Single Cell Analysis in Forensic Science: Exploring the Opportunities

Description:

This workshop will introduce single cell DNA (scDNA) analysis to the forensic community. Single-cell data has innumerable strengths including removing challenges associated with mixture interpretation. We will explore the advantages of scDNA analysis such as the absence of multiple contributors, contributor ratios, and allele masking. We will define key elements of single cell analysis and provide perspective on the workflow and possibilities of scDNA analysis by highlighting several studies, recovery and interpretation methods. In addition, with single-cell adoption being contingent on practical laboratory implementation strategies, we will include discussion about laboratory implementation and policy from the perspective of laboratory directors, technical leaders and practitioners.

 

Learning Outcomes:

  • Define single-cell analysis, understand its advantageous role in forensic science and illustrate a forensic single-cell workflow.
  • Become aware of common commercially available isolation techniques while highlighting the advantages and disadvantages of each;
  • Learn how to interpret single cell data;
  • Introduce cogent validation designs and expected results for this data type and speak on future directions.

 

Intended Audience:

The audience should include forensic DNA analysts and laboratory leadership (at any point in their career) with an emphasis on those involved in laboratory or section decision making and procedural implementation.

Description:

This workshop will introduce single cell DNA (scDNA) analysis to the forensic community. Single-cell data has innumerable strengths including removing challenges associated with mixture interpretation. We will explore the advantages of scDNA analysis such as the absence of multiple contributors, contributor ratios, and allele masking. We will define key elements of single cell analysis and provide perspective on the workflow and possibilities of scDNA analysis by highlighting several studies, recovery and interpretation methods. In addition, with single-cell adoption being contingent on practical laboratory implementation strategies, we will include discussion about laboratory implementation and policy from the perspective of laboratory directors, technical leaders and practitioners.

 

Learning Outcomes:

  • Define single-cell analysis, understand its advantageous role in forensic science and illustrate a forensic single-cell workflow.
  • Become aware of common commercially available isolation techniques while highlighting the advantages and disadvantages of each;
  • Learn how to interpret single cell data;
  • Introduce cogent validation designs and expected results for this data type and speak on future directions.

 

Intended Audience:

The audience should include forensic DNA analysts and laboratory leadership (at any point in their career) with an emphasis on those involved in laboratory or section decision making and procedural implementation.

Pricing:


  • Standard Registration$275

Workshop currently at capacity. A waitlist is available to join on our registration page.

Brought to you by

Worldwide Association of Women Forensic Experts

Co-Chair

Michael Marciano

Syracuse University

Mike Marciano is a Professor of Practice and the Director for Research in the College of Arts and Sciences Forensic and National Security Sciences Institute at Syracuse University. His research focuses on the analysis and interpretation of low quality/quantity human and non-human DNA samples using both wet bench techniques and statistical/machine learning methods with emphasis on single cell DNA analyses.

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Co-Chair

Catherine Grgicak

Rutgers University

Catherine Grgicak (Gerg-i-chuck) is an Associate Professor and Henry Rutgers Chair of the Department of Chemistry at Rutgers University in Camden NJ, and serves as Program Director for the Forensic Science programs at the same institution. She received her M.S.F.S. from the University of Alabama at Birmingham, and her Ph.D. in Chemistry from the University of Ottawa. Her Laboratory for Forensic Technology and Integration (LFTDI) develops systems that improve forensically relevant data generating and interpretive systems.

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Jack Ballantyne

Professor of Chemistry, University of Central Florida

Jack Ballantyne is a Professor of Chemistry at the University of Central Florida (UCF) and the Director of the National Center for Forensic Science in Orlando, Florida. Prior to entering academia, he was a casework forensic scientist in Scotland, Hong Kong and New York. His current research projects include RNA profiling for body fluid and tissue identification, trace DNA analysis including single-cell genomics and mixture deconvolution and genomics applications in forensic genetics.

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Stephanie Stoiloff

Director, Miami-Dade Sheriff’s Office Forensic and Technology Division

Stephanie Stoiloff is currently the Director of the Miami-Dade Sheriff’s Office Forensic and Technology Division, overseeing the Information Technology Office, the Crime Scene and Evidence Bureau, and a full-service, accredited Crime Laboratory that provides forensic services for the Miami-Dade Sheriff’s Office, all municipal agencies in Miami-Dade County, and state and federal agencies, upon request.

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